Compatibility of drugs in syringe driver

2. Two Item Syringe Drivers. Use the table to check compatibility of 2 drug combinations, the dose must not exceed that stated in the table. All combinations are compatible with water for injection as the diluent and can be made up to a convenient volume (usually smallest) except where specifically stated (e.g. 23ml). il lam ≤ 5 mg e g e g l 10 mg cine e g e. Data are most often available on combinations of two drugs in a syringe driver, although some combinations of three or four drugs are compatible. The following combinations of three drugs may be incompatible: Cyclizine + haloperidol + hyoscine butylbromide: generally regarded as .  · The compatibility and stability of 28 combinations of diamorphine hydrochloride ( mg/ml) with cyclizine lactate ( mg/ml), eight combinations of diamorphine ( mg/ml) with haloperidol ( mg/ml) and eight combinations of all three drugs was assessed after storage in 1 ml polypropylene syringes. Samples were stored for periods up to seven days in the light Cited by:

For compatibility information, consult the Palliative are Formulary or the Syringe Driver ook, or contact your pharmacy department (if available) or Palliative Meds Info (see details below) for advice. onsider the pH of each drug. Drugs with similar pHs are more likely to be compatible. Numerous factors effect stability and compatibility including drug salt, strength, diluents, order of drawing up, temperature and infusion periods. In this guide, infusion durations are for 24 hours. Monitoring of the combined drugs in the syringe driver throughout the infusion period is advised. Data are most often available on combinations of two drugs in a syringe driver, although some combinations of three or four drugs are compatible. The following combinations of three drugs may be incompatible: Cyclizine + haloperidol + hyoscine butylbromide: generally regarded as incompatible.

Knowledge of drug compatibility is needed before mixing drugs. not feasible, for example, use of a syringe driver during palliative care. Part of the process should involve the checking of compatibility between different drugs, compatibility of medicines in syringe drivers. This book serves as a valuable reference source, providing a comprehensive review of syringe pump use and administration of drugs via CSCI.